Ambizan is a newly discovered glycosaminoglycan biopolymer:
Ambizan consists of the same disaccharide repeat as hyaluronic acid (hyaluronan) and heparosan, but linked differently.
Ambizan can be enzymatically synthesized in a size-defined manner.
The negatively charged backbone of Ambizan makes it highly water-soluble.
The low viscosity of Ambizan is ideal for many applications.
Ambizan is stable and long-lasting due to it's unique sugar linkages.
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Polysaccharides such as cellulose and amylose form the basis of the best chiral stationary phases (CSPs) currently on the market due to their helical nature and higher loading capacities compared to synthetic polymers.
The Weka biopolymer, Ambizan, is a newly discovered polysaccharide that is linked in the same manner as amylose and has a similar helical structure, but consists of a disaccharide repeat that affords useful chemical functionality. Unlike amylose, Ambizan can be enzymatically synthesized in a size-defined manner. The negatively charged backbone of Ambizan may also positively affect chiral separation ability. Additionally, the low viscosity of Ambizan is ideal for chromatographic applications.
A new generation of polysaccharide-based chiral stationary phases is coming soon...